15
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4212 | XMU-MP-1 | Hippo pathway | |
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2. | |||
T71901 | MP-1 | ||
MP-1 is a covalent inhibitor of fumarate hydratase (FH) that exhibits cytotoxicity dependent on FH. MP-1 engages a functional cysteine in the Zn-finger domain of the tRNA methyltransferase enzyme TRMT1. | |||
T12398 | MP7 | PDK1 inhibitor | PDK |
MP7 (PDK1 inhibitor) is a inhibitor of phosphoinositide-dependent kinase-1 (PDK1). | |||
T10419 | AV-412 | MP412 | EGFR |
AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM). | |||
T69977 | BC-1485 | ||
BC-1485 is a first-in-class inhibitor of Fibrosis-inducing E3 ligase 1 (FIEL1 ), which disrupts FIEL1-directed PIAS4 ubiquitination. | |||
T80667 | 2-Methyl-1-Pyrroline | Others | |
2-Methyl-1-Pyrroline (2-MPN) is an intermediate of a photochemical dye that induces the formation of (R)-2-MP. | |||
T6999 | Teneligliptin hydrobromide | Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide) | Others , Proteasome , DPP-4 |
Teneligliptin hydrobromide (MP-513 (hydrobromide)) is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 ... | |||
T8445 | PU02 | PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine | Apoptosis , 5-HT Receptor |
PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor. | |||
T18365 | Mp-polymer ester | Others | |
Mp-polymer ester is a noncleavable antibody-drug conjugates (ADCs) linker typically employed in the synthesis of ADCs[1]. | |||
T37522 | Teneligliptin | ||
Teneligliptin (MP-513) is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM. Teneli... | |||
T18364 | Tesirine | MP-PEG8-VA-PABC-PBD Dimer | Others |
MP-PEG8-VA-PABC-PBD Dimer is a drug-linker conjugates for ADC which is used in the treatment of several cancers. PBD Dimer is a DNA alkylating which inhibits DNA replication[1]. | |||
T38915 | Antibacterial agent 32 | ||
Antibacterial agent 32 exhibits potent antimicrobial activity against E. coli strains NCTC 13351, M 50, and 7 MP, with minimum inhibitory concentration (MIC) values of 1 mcg/mL, 2 mcg/mL, and 8 mcg/mL, respectively (WO20... | |||
T81753 | mp-dLAE-PABC-MMAE | ||
mp-dLAE-PABC-MMAE is an agent-linker conjugate for antibody-drug conjugates (ADCs) that incorporates the potent tubulin inhibitor Monomethyl auristatin E (MMAE). This compound is utilized in the synthesis of ADCs to deli... | |||
T36881 | NHC-diphosphate triammonium | ||
NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral poly... | |||
T36880 | NHC-diphosphate | ||
NHC-diphosphate, a phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) in its diphosphate form[1], serves as a potent antiviral agent. As a pyrimidine ribonucleoside, NHC effectively counters the repl... |